The collection of European paintings from the Renaissance and mannerist period is not large but is distinguished by works of high quality. The major work in this group, an altarpiece by Perugino (Pietro di Cristoforo Vannucci), is the largest painting by this artist in North America and was the subject of a recent colloquium titled “Who Wielded the Paintbrush?” (March 2006). An international group of scholars discussed the painting’s attribution and its relationship to other works by Perugino and his most accomplished pupils.